Post-Bac Job Listings

If you are interested in posting a position on our website, please contact Dr. Anna Babakhanyan.

Research Assistant, Tsankoy Lab, Mount Sinai, Posted Mar 24, 2020

Undergraduate Research Opportunity, Obsessive Compulsive Disorder Institute, McLean Hospital, Mar 3, 2020

Clinical Research Assistant, Beth Israel Deaconess Medical Center, Posted Feb 28, 2020

Research Associate, Kadoch Laboratory, Dana-Farber Cancer Institute/HMS/Broad Institute, Posted Feb 19, 2020

Genomics & Neuroscience Research Associate, NYU, Posted Feb 19, 2020

Research Assistant I, Beth Israel Deaconess Medical Center, HMS, Posted Feb 19, 2020

Clinical Research Specialist I, Labs of Cognitive Neuroscience, Boston Children’s Hospital, HMS, Posted Feb 19, 2020

Seaver Autism Center Research Coordinator, Mount Sinai School of Medicine, Posted Feb 19, 2020

Research Assistant, Wainger lab, MGH, Posted Jan 17, 2020

Clinical Research Coordinator, The Metabolism Unit, MGH, Posted Jan 17, 2020

Lab Tech/PhD Students/Scientist positions at Dr. Maxim Prigozhin Lab, MCB Department, Harvard University, Posted Jan 10, 2020

Research Assistant I, Boston Children’s Hospital, Posted Jan 2, 2020

Research Assistant, Demehri Laboratory, Center for Cancer Immunology, MGH/HMS, Posted Jan 2, 2020

Research Assistant, Harvard Medical School, Brigham and Women’s Hospital, Posted September 24, 2019

Research Associate, Dr. Xavier Lab, Broad Institute, Posted Aug 8, 2019

Neurobiology Research Assistant, BIDMC Department of Neurology, Posted July 17, 2019

Research Coordinator, Cognitive Neuroscience Group, MGH Institute of Health Professions, Posted July 1, 2019

Staff Research Associate I: Microbiology and Immunology, UCSF, Posted June 4, 2019

Research Assistant, Van Hooser Lab, Brandeis University, Posted April 23, 2019

Full Time Clinical Research Coordinator, Dept. of Psychiatry, MGH, Posted April 23, 2019

Full-Time Tech Position, Bernardo Sabatini Lab, Harvard Medical School, Posted April 15, 2019

Full Time Research Assistant, Meenakshi Rao Laboratory, Boston Children's Hospital, Posted April 2, 2019

Research Technician, Sharma Lab, Infectious Diseases Institute, Ohio State University, Posted March 27, 2019

Full Time Research Assistant, Hormoz Lab at Harvard Medical School and Dana-Farber Cancer Institute, Posted March 27, 2019

PostBac opportunity in programming cellular function, Church Lab, HMS, Posted March 27, 2019

Laboratory research coordinator, Georgetown University, Posted March 19, 2019

Research Assistant, Wainger lab, MGH, Posted Mar 8, 2019

Research Assistant, Lehtinen Lab, Boston Children's Hospital, Posted Mar 8, 2019

Clinical Research Coordinator, The Program in Nutritional Metabolism, MGH, Posted Feb 21, 2019

Biomedical Research Assistant, Rockefeller University, Posted Feb 7, 2019

Clinical Research Assistant, The Movement Disorder Center, Beth Israel Deaconess Medical Center, Posted Jan 28, 2019

Clinical Research Assistant, Neurological Disorders, Beth Israel Deaconess Medical Center

Wellness Works Assistant Coordinator, Beth Israel Deaconess Medical Center, Posted Jan 28, 2019

Laboratory Research Assistant, Beth Israel Deaconess Medical Center, Posted Jan 28, 2019

Laboratory Research Assistant I, Beth Israel Deaconess Medical Center, Posted Jan 28, 2019

Clinical Research Coordinator II, Massachusetts General Hospital, Posted Jan 28, 2019

Staff Research Associate (SRA)/Specialist, UCSF, Posted Jan 28, 2019

Available starting Spring 2019: Two full-time, twoyear Neurobiology Research Assistant positions, Boston Children's Hospital, Posted Jan 28, 2019

 

 

Research Assistant, Tsankoy Lab, Mount Sinai

Alexander Tsankov, Ph.D. Assistant Professor of Genetics and Genomic Sciences  Icahn School of Medicine at Mount Sinai, New York, NY  atsankov@broadinstitute.org | www.tsankovlab.org

 

Position Description

We are looking for highly motivated, detail-oriented individuals genuinely interested in research bridging medicine and genomics to join the newly established Tsankov lab at the Icahn School of Medicine at Mount Sinai in New York City. Our lab’s overall vision is to build data-driven, quantitative models that improve diagnosis, find new drug-able pathways, and personalize treatment of patients with lung cancer and respiratory diseases. We process and analyze clinical samples from patients with the goal of unraveling the underlying regulatory mechanisms in normal lung cell homeostasis and interactions with the immune and stromal microenvironment as well as elucidating changes in cellular and tissue regulation in individuals with lung disease. New lab members have the option of being cross-trained to apply and

develop computational frameworks and experimental techniques for high-throughput, next generation sequencing (NGS) datasets (e.g. single-cell transcriptomic, epigenomic, and spatial data). The vibrant, multidisciplinary training environment will allow for learning the state-of-the art in single cell genomics analysis/technologies and for close interactions with clinical scientists and our collaborators at Mount Sinai, the Broad Institute, and Harvard Medical school.

Job responsibilites:

Process and analyze NGS and other biomedical data using established pipelines.

Develop and benchmark new tools for NGS and single cell data analysis.

Collaborate with researchers in interpretation of data.

Participate in the preparation of manuscripts, grants, and presentations.

Requirements:

BS, MS, or Ph.D. in computer science, comp bio, or other quantitative discipline.

Team oriented with abilities to think creatively and work independently.

Excellent written and verbal communication skills.

Programming/scripting skills in R, Matlab, Python/Jupyter, Perl, Unix, and/or LSF.

Training in machine learning, statistical modeling, and NGS genomic analysis a plus.

A genuine love for science and people.

Interested applicants please send 1) your CV with a list of publications and research

experiences, 2) a short summary of your present and future research interests, and 3) for

postdocs a list of three references and their contact information to Alex Tsankov

(atsankov@broadinstitute.org).

Mount Sinai offers numerous career development opportunities and benefits, including subsidized housing for students and postdocs, recreational programs/activities, excellent health, dental, and vision insurance. Compensation will be commensurate with experience. For more information please visit our lab’s website, www.tsankovlab.org.

Thank you for your interest in our lab!

Posted Mar 24, 2020

 

Undergraduate Research Opportunity, Obsessive Compulsive Disorder Institute, McLean Hospital

Contact information: Jacob Nota, PhD, Department of Psychiatry, Harvard Medical School, jnota@mclean.harvard.edu, McLean Hospital, https://www.mcleanhospital.org/programs/ocd-institute

Project description and duties: Research examining the relations between biological circadian rhythms, sleep, and obsessive-compulsive disorder (OCD; https://www.ncbi.nlm.nih.gov/pubmed/25603315). This new line of research represents a novel pathway to understanding and treating one of the most disabling mental health disorders. The study involves collection of saliva samples in order to measure biological circadian rhythms in individuals participating in intensive residential treatment for OCD. The research assistant will spend approximately 8 hours a week facilitating data collection, documentation, and assisting with subsequent data cleaning/analysis. Because of the necessities of the study, there is a need for availability during evening and night hours (e.g., between 18:00 and 04:00).

Skills required: Prior research experience is desirable but not required. Attention to detail and intrinsic motivation to be involved in research is required.

Learning outcomes: This position would be an excellent fit for applicants interested in obtaining doctoral training in clinical or counseling psychology or psychiatry, and/or preparation for research assistant positions after graduation. Mentorship is an important part of our mission, and our previous students have been accepted into top graduate schools and earned authorship on presentations and papers.

This project is ongoing and will be collecting data into the next academic year (2020-2021).  A minimum 8 hours per week commitment is needed (with these hours being able n the evening and night). For interested parties, up to 16 hours a week may be available. Students would be expected to begin training for the position by April 2020 and would be committing to work through summer 2020. For interested parties who are a good fit, it may be possible to continue the position in the academic year (2020-2021).

Mentoring: the student visitor will have the option to participate in weekly research meetings. The student will also meet with the principal investigator in one-on-one format.

Student stipend: Currently the position is not eligible for a stipend and is on a volunteer basis. Interested students are encouraged  to apply for Harvard fellowships: https://lifesciences.fas.harvard.edu/research-opportunities or research course credit

Application information: please send CV/resume  to: Jacob Nota, Ph.D. at jnota@mclean.harvard.edu

We will begin reviewing applicants immediately.

Posted Mar 3, 2020

 

 

 

Clinical Research Assistant, Beth Israel Deaconess Medical Center


The Movement Disorder Center at the Beth Israel Deaconess Medical Center, a Parkinson’s Foundation Center of Excellence is hiring a Clinical Research Assistant (CRA) to begin work approximately June of this year (2020). The CRA will work on clinical research projects studying medical and surgical treatment of neurological disorders including Parkinson's disease, dystonia, and essential tremor. Research responsibilities include: scheduling research subjects, preparing charts and lab supplies for subject visits, filing documentation related to research studies, recording research data on source documents and electronic databases, collecting and processing laboratory specimens, administering patient questionnaires, and assisting in patient recruitment. The position involves direct patient interactions when assisting with research study visits.

Administrative and other responsibilities include assisting with the completion of regulatory and Institutional Review Board documents, organizing logistics for center events, booking room reservations for center meetings, and assembling patient information folders. As a member of the interdisciplinary team, the CRA will be expected to attend team meetings and educational seminars, which may occasionally happen on weekends.

Interested applicants are asked if possible to commit to flexible volunteering hours during the 2020 spring semester, and transition into the full-time paid position in June of 2020, contingent on satisfactory performance during the volunteer period. The candidate must be willing to commit to the full-time CRA position for two years (or more).

Applicants should have a Bachelor's Degree in a health/science field (after graduation in May 2020), excellent organizational skills, computer literacy, an interest in clinical research, and the ability to function independently.  Good interpersonal skills are essential.

Interested candidates should please contact Dr. David K. Simon, MD PhD by email at dsimon1@bidmc.harvard.edu  and send a CV as well as a brief statement regarding your interest in the position.

 

Posted Feb 28, 2020

 

Research Associate, Kadoch Laboratory, Dana-Farber Cancer Institute/HMS/Broad Institute

Chromatin regulation in human disease

The Kadoch Laboratory at the Dana-Farber Cancer Institute, Harvard Medical School, and Broad Institute is seeking a highly qualified post-graduate student (student graduating with B.A. or B.S. this Spring/early Summer 2020) to join our vibrant research team as a Research Associate focused on cancer biology, epigenetics, and chromatin regulation. Our lab uses multidisciplinary approaches including biochemistry, biophysics, structural biology, chemical biology, and functional genomics to explore the mechanisms of chromatin remodeling complexes, which are frequently mutated in human cancers and other diseases. Our exciting and diverse set of projects involve collaborations across the Harvard and MIT centers in Boston and Cambridge. This is a unique opportunity with significant potential for the student to work closely with the PI as well as senior graduate students and postdoctoral fellows to carry forward independent projects resulting in both presentations and publications. 

The successful applicant will have advanced experience in molecular biology, protein biochemistry, structural biology, genetics and/or genomics-centered methodologies, through focused prior lab research experience (i.e. >2 years in research laboratories with strong letters of recommendation) as well as undergraduate coursework. We are looking for candidates who have at least two years of availability and who may be considering applying to graduate and/or medical school following their tenure in the lab. The ideal candidate will be exceptionally motivated, mature, detailed, goal-oriented, able to work both independently and in teams, and will possess excellent organizational, communication, and analytical skills.

Please contact Cigall Kadoch, Ph.D. directly at cigall_kadoch@dfci.harvard.edu for more information if interested (along with CV/resume) and please copy Dr. Kadoch’s assistant, Ms. Kristen Applegate, at kadochoffice@gmail.comWe will hire for this position(s) on a rolling basis over the next couple of months and will close the ad once positions have been filled.

For more information about our laboratory, please see the Kadoch Lab website at http://www.kadochlab.org, our recent publications (https://www.ncbi.nlm.nih.gov/pubmed/?term=kadoch+c), and news via our Twitter handles, @kadochlab, and @ckadoch.

Posted Feb 19, 2020

 

 

Genomics & Neuroscience Research Associate, NYU

Our lab at NYU School of Medicine is looking to hire a Research Associate starting this summer. The Evrony Lab is dedicated to understanding the mechanisms by which the genome builds the brain, and we are creating exciting new single-cell genomics technologies to identify the molecular–genetic defects underlying brain diseases whose causes are not known.
 
Research associates in the lab lead independent projects under the mentorship of the PI, and this can serve as a great place for building a portfolio of research accomplishments in preparation for applying to medical or graduate school.
 
You can read more about the lab at www.evronylab.org.


And you can apply here: https://jobs.nyulangone.org/job/10551073/research-associate-new-york-ny/

Posted Feb 19, 2020

 

 

Research Assistant I, Beth Israel Deaconess Medical Center, HMS

Grade: 05  Current Job Code: A1429

FLSA Status: Nonexempt - All per diem positions are considered Non-Exempt

Job Summary: Under supervision of the principal investigator, conducts a variety of routine experiments using molecular, cell biology, and/or biochemistry techniques. Records test results, calculates, transcribes, and analyzes data using basic statistics.

The candidate will work in an established basic science laboratory dedicated to understanding the molecular basis of ACTN4-mediated chronic kidney disease. Representative work has been published in Nature Genetics, Journal of Clinical Investigation, Proceedings of the National Academy of Sciences of the United States of America, and the Journal of the American Society of Nephrology (Kaplan et al., 2000, PMID:10700177; Kos et al., 2003, PMID: 12782671; Weins et al., 2007, PMID: 17901210; Henderson et al., 2009, PMID: 19357256; Ehrlicher et al., 2015, PMID: 25918384; Feng et al., 2018, PMID: 29378953). The laboratory utilizes a broad range of technologies, including human genetics, cellular assays, and mouse models. We also use innovative techniques involving induced Pluripotent Stem (iPS) cells engineering, organ-on-chips, mass spectrometry, and advanced microscopy. Primary responsibilities of this position include but are not limited to performing experiments for molecular, cellular, and animal studies that characterize kidney disease models. A successful candidate will have a strong interest in learning and applying these techniques toward bettering understanding kidney disease. Prior experience with animal studies is highly valued.

The following statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of this position.

Primary Responsibilities:

1.         Conducts routine tests following established procedures, which may include assays, DNA sequencing, tissue culture, protein purification, Western blotting, PCR analysis, electrophoresis, chromatography, etc. (essential)

2.         Uses standard research equipment such as microscopes, incubators, autoclaves, centrifuges, etc. (essential)

3.         Researches and collects basic study data through monitoring devices and maintains daily logs/basic records of methodologies and test results. With supervision, using databases, may summarize data and interpret results using descriptive statistics and basic hypothesis testing. (essential)

4.         May write standard operating procedures for documentation and make informal presentations of these procedures to others in the lab. (essential)

5.         Performs literature searches and library investigations as they relate to the research and/or as assigned. (essential)

6.         May demonstrate routine laboratory tasks to tests to students and other research personnel. (essential)

7.         Maintains own supplies and may be responsible for ordering supplies for the lab. (essential)

8.         Due to the dynamic environment in which research exists, must show flexibility in performing principal duties and responsibilities as research projects evolve. (essential)

9.         Attends Medical Center lectures regarding all safety requirements/conditions. Attends courses, lectures, and conferences to further own knowledge of research. (essential)

Required Qualifications:

1.         Bachelor's degree required in Biology, Biochemistry, Genetics, Engineering, Physiology, Life Science, or a related scientific field required.

2.         At least 0-1 years related work experience.

3.         Familiarity with basic laboratory instruments and equipment, computers (databases, spreadsheets, statistics) and scientific procedures.

4.         Basic familiarity with computers. Ability to navigate at a basic level within web-based applications.

Competencies:

1.         Decision Making: Ability to make decisions that are based on specific instructions, standard practices and established procedures which generally require little or no supervision.

2.         Problem Solving: Ability to address problems that are routine, somewhat repetitive and generally solved by following clear directions and procedures and by identifying opportunities for process improvements.

3.         Independence of Action: Ability to follow general instructions and procedures as provided. Work is monitored by supervisor/manager.

4.         Written Communications: Ability to read, and write in English in order to understand basic safety instructions and take direction from supervisors; communicate effectively with patients, families and other medical center staff; and respond to basic questions.

5.         Oral Communications: Ability to understand spoken English in order to follow basic safety instructions and take direction from supervisors; communicate effectively in basic English with patients, families and medical center staff in response to routine questions.

6.         Knowledge: Ability to demonstrate basic knowledge of fundamental concepts, practices and procedures with the ability to use them in routine situations. Specialized knowledge not required.

7.         Team Work: Ability to interact respectfully with other employees, professional staff and/or external contacts to offer ideas, identify issues, obtain information or deliver services.

8.         Customer Service: Ability to demonstrate a positive attitude and respond to requests in a timely and respectful manner.

Social/Environmental Requirements:

1.         Work needs to occur at an average pace with intermittent breaks. Requires an average amount of attention to maintain quality of work.

2.         Work is fairly routine from day to day. Employee follows a set pattern with any changes being communicated by supervisor.

3.         No substantial exposure to adverse environmental conditions

4.         Health Care Status: NHCW: No patient contact.- Health Care Worker Status may vary by department

Sensory Requirements: Close work (paperwork, visual examination), Visual clarity <3 feet, Conversation, Monitoring Equipment, Telephone, Background Noise.

Physical Requirements: Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move through out the hospital campus

Contact Person: Di Feng dfeng@bidmc.harvard.edu

This is a 2 year position and the start date is flexible.

Posted Feb 19, 2020

 

 

Clinical Research Specialist I, Labs of Cognitive Neuroscience, Boston Children’s Hospital, HMS

The Laboratories of Cognitive Neuroscience (LCN) at Boston Children’s Hospital are dedicated to furthering our understanding of brain and cognitive development in children diagnosed with or at risk for various developmental disorders. Our multidisciplinary team of researchers brings together experts from a wide range of fields, including neuroscience, psychology, and education. In collaboration with clinical experts in fields such as developmental pediatrics and child neurology, we are working to expand our knowledge of neurodevelopmental disorders. Through this collaborative and comprehensive approach, we aim to drive the science forward as rapidly as possible, so that we can translate what we learn into earlier identification, improved therapies, and better outcomes for children and families affected by developmental disorders.

The Clinical Research Specialist (CRS) will join the Emotion Project team in the Nelson Lab. The CRS will coordinate day-to day operations and functions for a longitudinal study investigating the neural bases of emotion processing in typically developing young children. The project uses electrophysiology, functional near infrared spectroscopy, physiology, eye tracking, and behavioral measures in a cohort of children being followed from infancy to 7 years of age. Responsibilities include working with, and coordinating a team of undergraduate students, postdocs, and research staff associated with the research project in addition to IRB management and preparing progress reports. Furthermore, the CRS will work closely with team members on the development, coordination, and implementation of research procedures, and will contribute to running the day-to-day operations for research protocols in the Labs of Cognitive Neuroscience under the direction of the Principal Investigator and the Program Manager.

 

Eligible candidates have the following qualifications:

  1. bachelor’s degree in psychology, cognitive science, neuroscience, or related field, as well as a 2-year commitment to the position
  1. working with infants or children in a research setting, preferably using physiological, behavioral or neuroimaging measures such as eye tracking, heart rate, EEG, or ERP
  1. least two years of paid professional experience working in a research setting with human subjects
  1. for flexible scheduling including evenings and weekends
  1. skills including working knowledge of PC and Mac operating systems, basic statistics software (e.g. Excel, SPSS), and basic experimental presentation and collection software (e.g., ePrime, Redcap, Matlab)
  1. to assist with grant preparation, publications, presentations and/or applications to an Institutional Review Board
  2. level of motivation; ability to work independently and as part of a team; excellent communication, organization, and attention to detail  

The estimated start for this position is Summer 2020. 

Please send a cover letter and CV to Anna Luke at anna.luke@childrens.harvard.edu.

 

Posted Feb 19, 2020

 

Seaver Autism Center Research Coordinator, Mount Sinai School of Medicine

Primary PI: Foss-­Feig

Description: We are looking to fill a full-­time research position in the Foss-­Feig Lab at the Seaver Autism Center for Research and Treatment at Mount Sinai. The Seaver Autism Center is a clinical research center focusing on the study of Autism Spectrum Disorders (ASD) through genetics, imaging, pharmaceutical, and neuropsychological research trials. The Foss-­Feig Lab combines clinical assessments with brain-­based methods, including EEG and MRI, to examine sensory and perceptual functioning in ASD. We also study the relation between ASD and other neurodevelopmental disorders, including schizophrenia and psychosis prodrome, as well as monogenic disorders associated with ASD.

 

The research coordinator’s primary responsibilities will include:

• Subject recruitment, screening, and scheduling for children, adolescents and adults with

autism spectrum disorder as well as typically developing controls

• Acquiring brain imaging (EEG, MRI) and eye-­tracking data in patient and control populations, including both operating hardware and software and managing participant behavior and comfort to optimize data quality during sessions

• Testing participants with standardized behavioral assessments (e.g., neuropsychological testing, sensory assessment batteries, self-­report and caregiver questionnaires)

• Developing and piloting experimental stimuli and program code

• Managing and analyzing behavioral and imaging datasets

• Preparing and maintaining IRB protocols

• Collaborating with other research coordinators and investigators at the Seaver Center and within the broader Mount Sinai community to engage families in multiple studies and creating an organized participant flow and coordinated research experience

• Recruiting and supervising undergraduate interns in assisting with data management

• Assisting with grant preparation and submissions 

 

Additional opportunities in which the research coordinated will be expected to participate:

• Grand Rounds and other community lectures

• Observations of clinical assessments by psychiatrists and psychologists, including standardized autism assessments, psychiatric interviews, and medical histories

• Conference abstract submissions and presentations

• Secondary analysis of existing EEG, fMRI, and behavioral data sets for publication

• Manuscript preparation and submission
 

  1. Interested applicants should possess a Bachelor's degree;; have a strong background in psychology, neuroscience, biological sciences, study methodology, and statistics
  2. have experience working with developmentally disabled children and adults;; have a strong interest in research;; be highly familiar and comfortable with widely available computer programs
  3. be interested in learning about etiology and treatment of psychiatric and neurodevelopmental disorders
  4. and be able and willing to work with psychiatric patients and their families in a professional and compassionate manner.

 

Interested applicants should send a CV and cover letter to Christopher McLaughlin at

Christopher.mclaughlin@mssm.edu.

Posted Feb 19, 2020

 

Research Assistant, Wainger lab, MGH

waingerlab.org

We are a young and vibrant group applying biological, physiological and computational tools to understand and identify new treatments for motor and sensory neuron diseases. The laboratory is seeking a motivated and enthusiastic research assistant with experience in molecular biology and in particular stem cell biology to support preclinical studies related to Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease) and pain. The research technician will contribute to the intellectual development of a project, attend and present at lab meetings, and engage in the scientific community through opportunities to attend conferences and publish papers. The major responsibilities will include stem cell culture and differentiation, analysis of molecular disease-related phenotypes using patient and control as well as gene-edited iPSC lines, quantitative analysis of expression and sequence data, general molecular biology techniques such as immunohistochemistry, RNA isolation and PCR to analyze cells of interest. Additional work will include assistance with ordering, laboratory maintenance and animal husbandry. The candidate must be able to make a two-year commitment.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

  • Stem cell culture and differentiation
  • High-content imaging and physiology (calcium imaging/ optogenetics)
  • Bioinformatic analysis of expression and sequence data
  • Mouse brain and spinal cord dissection
  • Purification of RNA and PCR
  • Perform tasks associated with ordering, animal husbandry, and lab uptake
  • Grant applications & protocols for Biosafety, Animals, and IRB
  • May assist with training other personnel

SKILLS/ABILITIES/COMPETENCIES REQUIRED: Must be an enthusiastic, diligent and professional team player with excellent time management skills. Meticulous detail about laboratory techniques and documentation are required, as are the ability to work independently and as a member of a team. The candidate must possess excellent verbal and written communication skills. The position requires accurately maintaining records of laboratory work in sufficient detail for reproduction of the experiments, organizing, analyzing and summarizing acquired data. The candidate may assist with drafting or contributing to the preparation of research papers, manuscripts or other documents for publication and/or presentation.

EDUCATION: BA/BS in neurobiology, molecular biology, or related field

EXPERIENCE: One year of previous relevant laboratory work experience desired.

PLEASE CONTACT AND INCLUDE COVER LETTER, CV, AND TRANSCRIPT:

brian.wainger@mgh.harvard.edu

Posted Jan 17, 2020

 

 

Clinical Research Coordinator, The Metabolism Unit, MGH

Opportunity Description: The Metabolism Unit (MetU), a clinical research unit at Massachusetts General Hospital, is seeking highly motivated college graduates for a two-year position as a Clinical Research Coordinator (CRC). The MetU specializes in advancing our knowledge of the complex interplay between metabolic disorders, cardiovascular disease, and the gastrointestinal system. Models include generalized obesity, fatty liver disease, and HIV-infected patients with dysfunctional adipose tissue.  For example, people who have HIV, with inflammation and altered body composition, are twice as likely to develop heart disease during the course of their lifetime. Through the conduct and analysis of clinical trials at MGH, MetU researchers have made major contributions to our understanding of this phenomenon.

CRCs at the MetU have the opportunity to work on clinical research that is rewarding and has far-reaching implications. Working as a part of a team, CRCs are responsible for facilitating the long-term success of a research trial in several ways. These include:

Conducting patient visits at the MGH Clinical Research Center and other hospital sites

Facilitating the screening and recruitment of new patients

Collecting and managing data

Performing structured patient interviews

Ensuring compliance with various regulatory bodies such as the MGH Institutional Review Board

Hardworking and ambitious coordinators may also have the chance to contribute to the preparation of manuscripts for authorship/publication.

 This position is ideal for a diligent pre-medical graduate who is looking to gain significant research experience in a clinical setting before enrolling in medical school. CRCs at MetU have a high degree of responsibility. The ability to prioritize tasks is important. The successful candidate will also demonstrate a meticulous attention to detail and strong interpersonal skills. A background in statistics/research/clinical settings is desirable but not required.

 This is a paid position. CRCs will work 40 hours per week. CRCs will likely be expected to start by late May or early June.

How to Apply: To apply online, please go tohttps://www.massgeneral.org/careers/jobsearch.aspx and enter job number 3117279. After you have applied online, please email Pamela Yurrita directly atpyurrita@mgh.harvard.edu  with a CV and cover letter describing your background and interest. Applicants will be considered on a rolling basis.

Posted Jan 17, 2020

 

 

Dr. Maxim Prigozhin Lab, MCB Department, Harvard University

Quantitative Biology Initiative, Department of Molecular and Cellular Biology, Department of Applied Physics, Harvard University

MULTICOLOR AND TIME-RESOLVED ELECTRON MICROSCOPY OF CELL SIGNALING

KEYWORDS: biophysics, optics, single-molecule fluorescence, single-particle electron microscopy, cryo-EM, cathodoluminescence, nanoparticles for biology, cryo-vitrification, time-resolved vitrification, cell signaling, GPCRs, neuroscience Electron microscopy is an ideal imaging technique to study biological cells at the nanoscale. However, typically electron microscopy only provides static black-and-white images. In an effort to enable multicolor and time-resolved electron microscopy, my lab will develop dedicated molecular probes and instrumentation for new correlative light and electron microscopy modalities, and build next-generation biophysical tools for timeresolved cryo-vitrification and high-resolution imaging of cells. These methods will be used to elucidate the nanoscale protein and membrane dynamics of G protein-coupled receptor (GPCR) signaling in differentiated cells and complex tissues.

CURRENTLY RECRUITING technicians, PhD students, postdocs, visiting scholars and other scientists interested in the following RESEARCH AREAS:

1) Instrumentation development for single-particle fluorescence and electron

imaging

2) Synthesis, functionalization, and biological applications of nanoparticles

3) Cell biology of GPCR signaling and of neural transmission

If you are interested in joining or have other questions, please contact Max Prigozhin at

maxim_prigozhin@harvard.edu. Graduate students are encouraged to apply through

the following PhD programs at Harvard:

· Molecules, Cells, and Organisms

· Applied Physics

· Systems, Synthetic, and Quantitative Biology

In your application, please indicate your interest in pursuing your PhD work with Max.

Posted Jan 10, 2020

 

 

Research Assistant I, Boston Children’s Hospital

Job Description

A full-time laboratory Research Assistant position is currently available with Dr. Christopher Yuskaitis, Co-Director of the Infantile Spasms Program and Instructor of Neurology at Boston Children’s Hospital. Dr. Yuskaitis’ research program focuses on genetic models of epilepsy associated with nutrient sensing in the brain utilizing cell culture and animal models. We are seeking an enthusiastic, detail-oriented individual to assist with basic science and translational research projects.

This Research Assistant I will be responsible for:

Generating, maintaining, and genotyping transgenic mouse lines.

Performing a variety of routine and specialized laboratory procedures, including DNA extraction, PCR, gel electrophoresis, and other relevant procedures, as necessary.

Planning and performing behavioral assays.

Maintaining neuron and fibroblast cultures and performing in vitro experiments.

Performing molecular biology and biochemical assays on cell and mouse samples.

Communicating regularly with lab members to discuss experimental results and to collaborate on completion of tasks.

Participating in laboratory meetings and presentations.

 

To qualify, you must have:

  • Bachelor’s degree in neuroscience, biology, or related field. 
  • Experience working with rodent models in a research environment.
  • Excellent problem-solving skills. 
  • Strong organizational and communication skills. 
  • Flexibility for occasional rotating weekend work.

Preference will be given to highly-qualified applicants who can start as soon as possible. A two-year commitment is strongly preferred. The Sahin Lab has an excellent track record of previous research assistants who have gone on to graduate and medical school.

This is a full-time, salaried position with affordable health, vision and dental insurance, generous levels of time off, 403(b) retirement savings plan, pension, tuition reimbursement, cell phone plan discounts, and discounted rates on T-passes (50% off).

If you are interested please email your resume and cover letter to the address listed below.

Dr. Christopher Yuskaitis

Christopher.Yuskaitis@Childrens.Harvard.edu

Posted Jan 2, 2020

 

 

Research Assistant, Demehri Laboratory, Center for Cancer Immunology, MGH/HMS

Full time research assistant position is available immediately in our laboratory at Massachusetts General Hospital/Harvard Medical School to study the mechanisms of immune regulation of early cancer development and the role alarmins and commensal viruses in this process. The position is ideal for a recent graduate planning to work for couple of years in research before entering graduate or medical school. Besides bench research, applicant will have the opportunity to learn about clinical care for patients with severe skin cancers and skin-related adverse effects of cancer immunotherapies. Attention to detail, high motivation, and effective communication skills are essential. Knowledge in immunological, molecular, and mice experimentations are considered important for this position.

Visit our laboratory website for more detail:

http://massgeneral.link/DemeheriLab

Please email a cover letter and CV to Dr. Shawn Demehri:

sdemehri1@mgh.harvard.edu

Posted Jan 2, 2020

 

Research Assistant, Harvard Medical School, Brigham and Women’s Hospital

A research assistant position is available in the Division of Cardiovascular Medicine at Brigham and Women’s Hospital and Harvard Medical School in the laboratory of Dr. Paul B. Yu.

Our laboratory performs translational research with the goal of understanding how context-sensitive bone morphogenetic protein (BMP) and transforming growth factor-β (TGF- β) signals are transduced by target cells, and how abnormalities of signal transduction and downstream regulation may lead to abnormal vascular cell function, pulmonary arterial hypertension, and musculoskeletal disease. Our work lies at the nexus of progenitor cell biology, chemical biology, cardiovascular physiology, and experimental pharmacology.

We have developed novel animal models of disease, chemical probes and experimental therapeutics geared towards understanding mechanisms of BMP and TGF- β signaling and treating vascular and musculoskeletal disease. This work has led to novel treatment strategies that will enter the clinic. The candidate will be trained in basic science and translational study methods, and potentially work with patients in the context of 2 different clinical studies.

Recent high-profile publications from our lab include:

https://www.ncbi.nlm.nih.gov/pubmed/30312106

https://www.ncbi.nlm.nih.gov/pubmed/27881824

https://www.ncbi.nlm.nih.gov/pubmed/27115515

https://www.ncbi.nlm.nih.gov/pubmed/26461965

https://www.ncbi.nlm.nih.gov/pubmed/26333933

https://www.ncbi.nlm.nih.gov/pubmed/26076038
 

We welcome applications from highly motivated, independent and entrepreneurial-minded individuals with an interest in developing their skills in biology and science towards careers in the Health Sciences, or Drug Development. Previous trainees have launched successful careers following their work in the laboratory with Medical School and Clinical training, Graduate School Ph.D. studies, Medical and Research Faculty Positions, Biotech and Pharma Industry positions, and Health Care Venture Capital.

REQUIRED SKILLS AND EXPERIENCE

A recent undergraduate degree in Biological Sciences, Chemistry or Physics

Excellent written and verbal communication skills in English

Some experience with tissue culture, and molecular biology is preferred.

Excellent organizational skills

Interested applicants please send a cover letter, curriculum vitae and the names and contact information of at least 3 references to signaling@gmx.com.

 

Posted Sep 24, 2019

 

Research Associate, Dr. Xavier Lab, Broad Institute

The Xavier Lab is looking for a Research Associate to contribute to its research on adaptive immunity in inflammatory bowel disease.

The ideal candidate is a highly motivated individual looking to be part of a dynamic, collaborative team that is developing cutting-edge technologies in mucosal immunology and antibody research. The candidate should be interested in active engagement in experimental design and be able to troubleshoot experiments.  This position provides an excellent opportunity to any person interested in pursuing a career in medical research, molecular immunology, antibody discovery, and intestinal health.

Dr. Ramnik Xavier is a Professor of Medicine at Harvard, Co-Director of the Microbiome and Infectious Disease Program at the Broad Institute and Director of the Center for Computational and Integrative Biology at MGH. He is a world leader in inflammatory bowel disease research and has an outstanding track record of publishing seminal papers including PMID: 30392957, PMID:30356183 and PMID:30630933.

Duties and Responsibilities:

  • Collaborate with other lab members to successfully develop and execute protocols including cloning and production of monoclonal antibodies from B cells.
  • Actively engage in experimental design and able to troubleshoot experiments.
  • In collaboration with other lab members develop and perform functional assays to test the interaction between antibodies and the microbiome.
  • Successfully keep an organized lab notebook of all experimental efforts.

Requirements:

  • A Bachelor’s degree or Master’s degree in Microbiology, Molecular Biology, Genetics, Biochemistry, or other related field.
  • Experience with molecular biology techniques (e.g. tissue culture, PCR, cloning, DNA/RNA extraction, etc.).
  • Able to work collaboratively, as well as independently.
  • Excellent critical thinking, communication, and organizational skills.

https://broadinstitute.wd1.myworkdayjobs.com/broad_institute/job/Cambrid...

The Broad Institute will not offer Visa sponsorship for this opportunity.

Posted Aug 8, 2019

 

 

Neurobiology Research Assistant, BIDMC Department of Neurology

Job Description: We are looking for an enthusiastic and experienced Research Assistant with a background in neurobiology who would like to apply a wide variety of research techniques.  Our laboratory investigates the neurobiology of sleep; in particular, we hope to identify the neurotransmitters and neural pathways that underlie narcolepsy and other sleep disorders.  The Research Assistant will use methods including immunohistochemistry, PCR and other molecular biology techniques, mouse colony management, rodent surgery, and physiologic recordings of sleep. The applicant should also have good organizational skills for ordering supplies and basic lab management. Ideally, the applicant will join our lab for at least 2 years.

Qualifications: BS or MS with college coursework in neurobiology, biology, and chemistry. At least 1 year of full time laboratory experience in immunohistochemistry, PCR, and research with rodents is preferred. 

Wage: dependent on experience:

Days/Hours: 5 days/week, 8 hours/day, with some flexibility for independent workers

Start date: Aug 1, 2019, but flexible.

Company Description: Beth Israel Deaconess Medical Center is a Harvard-affiliated teaching hospital with a long tradition of excellence in cutting-edge research.  We are located in the Longwood medical area of Boston, the most active biomedical research community in the world.  The BIDMC Department of Neurology performs research on a variety of topics involving neuroanatomy, neurophysiology, neural development, and neurodegeneration.

Please apply on-line at:   http://jobs.bidmc.org/     and search for: job # 30839BR

Also, please email your cover letter and C.V. to: Tom Scammell, M.D., Professor of Neurology    tscammel@bidmc.harvard.edu
Posted July 17, 2019

 

 

Research Coordinator, Cognitive Neuroscience Group, Learning and Development (LEAD) team, MGH Institute of Health Professions

Contact information: Dr. Yael Arbel, co-director Cognitive Neuroscience Group, Department of Communication Sciences and Disorders, MGH IHP, 79 13th Street, Boston, MA 02129. CNGLEAD@MGHIHP.EDUhttps://www.mghihp.edu/research/cognitive-neuroscience-group

Position description: A research coordinator is needed for federally funded projects to study neural function associated with cognition and learning in typically developing children and children with developmental language disorders. The projects involve the recording and analysis of Event Related Potentials (ERPs) extracted from EEG recorded from the scalp, and the administration and analysis of cognitive and language tests. Technical skills to support data analysis are of major importance.

Anticipated start date: 8/19/2019

Work Schedule:           40 hours per week

PRINCIPAL DUTIES AND RESPONSIBILITIES:

1)         ERP signal processing and data analysis using Excel, MATLAB, and SPSS/R

2)         ERP and behavioral data collection

3)         Training and providing technical support for lab personnel

4)         Additional responsibilities may include, but are not limited to: conducting literature reviews, organizing and maintaining databases, behavioral and electrophysiological data collection, recruitment of participants, managing of IRB protocols

EDUCATION AND EXPERIENCE QUALIFICATIONS

Requirements: bachelor’s degree in a scientific or social science/education field. The candidate must have experience with MATLAB and Excel coding, and with statistical analysis. Previous research experience with ERP research is preferred. Relevant coursework in psychology or neuroscience, and statistics, is desired. Prior experience with database management software (e.g. RedCap), and Eprime software for task design is also helpful. The candidate must be self-motivated, independent, mature and able to work in a fast-paced, challenging environment. This position will provide invaluable experience for anyone interested in pursuing graduate study in the fields of communication sciences and disorders, medicine, experimental psychology, educational psychology or cognitive neuroscience.

SKILLS/ ABILITIES/ COMPETENCIES REQUIRED        

Excellent communication skills (verbal and written), ability to work independently and in a team. Preferred skills include: coding in MATLAB and excel, signal processing, eye-tracking data analysis, statistical analysis using SPSS or R, Excel. No research experience is required.

Posted July 1, 2019

 

 

 

Staff Research Associate I: Microbiology and Immunology, UCSF

Full Time position, 52218BR

Under direct supervision and training, the Staff Research Associate I (SRA I) will be working as part of a multidisciplinary group to support our studies of novel immune cell-based cancer immunotherapies. The SRA I will utilize various protocols to generate the molecular components, such as DNA constructs, necessary for specific cellular engineering experiments. Additional responsibilities will consist of isolation and culture of primary human immune cells, as well as functional analysis of engineered cells via Sanger sequencing, next-generation DNA sequencing, and flow cytometry.

This position represents an excellent opportunity to gain exposure to basic laboratory skills as well as genetics and genome engineering skills in a dynamic, well-established research environment.

Required Qualifications

• BA/BS degree – obtained by or prior to time of hire – in a related science and knowledge of, or experience with, the basic techniques or methods required by the position; or an equivalent combination of education and experience

• Candidates must meet the requirements by the time of appointment

• Willingness and ability to learn new methods and skills for changing research priorities

• Ability to work independently and as a member of a research team

• Strong interpersonal communication skills (verbal and written)

• Strong organizational skills

• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines

Preferred Qualifications

• Prior experience with DNA sequencing technologies, including Sanger and NGS (can be acquired while in school)

• Prior experience in the design and assembly of DNA constructs (via restriction digestion and ligation, Gibson assemblies, Golden-Gate assemblies, etc. Can be acquired while in school)

• Prior hands on experience with mice handling and injections helpful (can be acquired while in school)

• Prior experience with cell culture (can be acquired while in school)

• Prior experience in writing reports to include methods / protocols / procedures, results and tentative conclusions (can be acquired while in school)

More details https://sjobs.brassring.com/TGnewUI/Search/Home/Home?partnerid=6495&siteid=5226#jobDetails=2846598_5226

Posted June 4, 2019

 

 

Research Assistant, Van Hooser Lab, Brandeis University

The Van Hooser lab at Brandeis University is seeking a research assistant for a 1-3 year position. The lab studies the development and function of visual cortical circuits using brain imaging (in vivo 2-photon microscopy and intrinsic signal imaging), electrophysiological techniques, and optogenetic methods (vhlab.org).

Duties: The primary responsibility of this position is to help the laboratory complete basic science experiments. The research assistant will conduct animal experiments to uncover fundamental principles of neural development using 2-photon imaging, intrinsic imaging, and multichannel electrophysiology, and/or analyze data using MATLAB. This is an opportunity for an enthusiastic, hard-working individual to rapidly gain experience with animal surgery and advanced neuroscience techniques. It is expected that these experiments will result in authorship on research publications.

Requirements: BS/BA/MA in a scientific or engineering discipline. Some experience with small animal surgery, physiology, or computer programming is desired. Start date May-July 2019. Members of groups that are underrepresented in science are strongly encouraged to apply.

Brandeis University is located 10 miles west of Boston in Waltham, Massachusetts, and is 20-30 minutes from Boston or Cambridge by train or car. The life sciences community at Brandeis is highly interactive, with opportunities for learning about work in many labs through seminars and cross-lab collaborations (www.brandeis.edu/neuroscience).

To apply, please send a cover letter, CV or resume, and the names of 2-3 references to Steve Van Hooser, vanhoosr@brandeis.edu.

Posted April 23, 2019

 

 

Full Time Clinical Research Coordinator, Dept. of Psychiatry, MGH

The Massachusetts General Hospital Department of Psychiatry is seeking fulltime clinical research coordinators to assist with the operation of current, ongoing research studies as well as assist with the operation of future studies. Primary responsibilities include implementing study protocols, administering neuropsychological tests to elderly subjects with or without cognitive problems, maintaining accurate documentation, and assisting with other research tasks as needed. We are seeking highly motivated clinical research coordinators with the strong interpersonal skills necessary to interact with elderly subjects. The ideal applicant should have the drive and enthusiasm to be an integral part of a team that is working to better understand aging and neurodegenerative diseases.

Here is the link to the job application: https://www.massgeneral.org/careers/jobsearch.aspx

Olivia Umoren, Clinical Research Coordinator II
Community Organizer, CARE Research Center
Massachusetts General Hospital
Alzheimer's Disease Research Center
149 13th Street, Suite 2683
Charlestown, MA 02129
P: 617-726-0493 | olivia.umoren@mgh.harvard.edu

Posted April 23, 2019

 

 

Full-Time Tech Position, Bernardo Sabatini Lab, Harvard Medical School

In the Sabatini lab, we are seeking a full-time technician to run in vivo optogenetic experiments to identify which brain circuits underlie associative learning and how changes in neural circuits encode learning.

To study the synaptic and neural circuit changes that underlie learning, we train mice using an optogenetic manipulation to indicate the availability of a food pellet.

50% of the time: mouse behavior and optogenetics

Technician will be primarily responsible for running the cued reaching behavior. This is a head-fixed behavior that proceeds in 3 steps: 1. Reach training – manually training each mouse to reach for food pellets while head-fixed

This is a “hands-on” step that requires interaction with the animal and some sensitivity to the animal’s internal state. 2. Cue training – pairing the optogenetic cue with presentation of a food pellet

This is trained using an automated behavior set-up. The technician will have to upload code to the Arduino-controlled behavior set-up, adjust behavior task parameters dependent on an animal’s performance to accomplish training, and verify/troubleshoot problems with the behavior set-up.

3. Optogenetic or pharmacologic manipulations – neural interventions to test the involvement of different brain areas in the behavior

Technician will run experiments to map out brain circuits involved in the behavior. The current system can accommodate 12-16 mice per afternoon running in parallel. Technician should be able to schedule and manage multiple training sessions in parallel. General organization skills will be sufficient for this.

25% of the time: data analysis

Applicants should have an interest in learning how computer vision can be applied to mouse behavioral data, specifically, tracking the forepaw of the mouse using high-speed video (260 frames per second) and in 3D.

15% of the time: histology

Technician will process post-mortem brain tissue for imaging on a microscope.

10% of the time: mouse husbandry

Technician will maintain the transgenic mouse lines required for these experiments.

Applicant should be organized and detail-oriented, have some background in neuroscience (preferably undergraduate degree in neuroscience or similar), references, previous lab experience, and an interest in running and troubleshooting complex behavioral experiments.

Other relevant skills:

· Applicant should be familiar with how to keep an organized, up-to-date and comprehensive daily lab notebook.

· Applicant should be able to schedule his/her own time to accomplish multiple experiments within a single day (e.g., tissue histology in the morning, mouse behavior in the afternoon).

· Applicant should be familiar with Google sheets.

· Previous experience in perfusions and/or tissue histology is helpful but is not necessary.

· Applicant should be able to focus for long periods of time on specific tasks. This focus is particularly important for the early stages of mouse training.

· Applicant should be conscientious about taking notes and carefully following and setting up standard operating procedures (SOPs).

· Some introductory familiarity with Arduino may be helpful but is not required.

· Previous experience with animal behavior will be helpful but is not required. (Pet/dog training is relevant here.)

· Introductory coding experience may be helpful but is not strictly required.

· Applicant should be interested in learning new lab skills.

· Applicant should be curious about our neuroscience research goals and interested in learning more about the field through bi-monthly discussions of recently published papers in neuroscience.

· Applicant should be interested in attending weekly research seminars and lab meetings.

· Applicant should be able to work independently and troubleshoot basic problems.

· Applicant should be interested in learning and setting up new lab procedures with some help.

· Applicant should have an organized approach to his/her work.

· Applicant should be open to increasingly independent and varied projects, as lab skills are gained and experimental expertise increases.

Contact: If interested in applying, please contact kr112@hms.harvard.edu with resume and references.

Posted April 15, 2019

 

Full Time Research Assistant, Meenakshi Rao Laboratory, Boston Children's Hospital

Lab overview: The laboratory of Meenakshi Rao, M.D., Ph.D. seeks a highly motivated individual excited about science to join our team as a full-time research assistant. The gastrointestinal (GI) tract is unique among other organs because it has its own intrinsic nervous system, called the enteric nervous system (ENS). The ENS is large, complex, and regulates a variety of digestive and metabolic functions. The Rao lab uses mouse genetic models, imaging, and a variety of both in vivo and ex vivo assays to investigate how information about nutrients, mechanical stimuli, and microbes is detected and used by neurons and glia of the ENS to regulate GI motility, metabolism, epithelial functions and immune responses.

This is an outstanding opportunity to gain research experience and author publications in an exciting area at the interface of neuroscience and digestive biology.

Job description: The research assistant will work closely with the principal investigator and postdoctoral fellows to perform experiments that involve tissue dissection, qPCR, microscopy, immunohistochemistry, rodent surgeries and behavioral assays. 25% of time will be dedicated to maintaining the mouse colony and administrative responsibilities, such as ordering supplies.

Minimum Degree Required: B.A. or B.S. with major in Neuroscience, Biology, Biochemistry or Biomedical Engineering. Other majors considered depending on relevant experience and coursework.

Minimum Qualifications: Excellent organizational skills, prior full-time work experience, and good written as well as verbal communication skills in English.

Preferred Qualifications: At least 1 year prior research lab experience. Experience working with mice, molecular biology, tissue culture, or calcium imaging would be highly preferred.

Interested? Please send a C.V., cover letter describing prior experience, and contact information for 2-3 references to Meenakshi.Rao@childrens.harvard.edu.

 

Posted April 2, 2019

 

Research Technician, Sharma Lab, Infectious Diseases Institute, Ohio State University

Sharma Laboratory, Center for Retrovirus Research, Infectious Diseases Institute, Ohio State University

Job Title: Research Technician

Start Date: Flexible

We are looking for an independent and highly motivated candidate to join our research group focused on studies of retrovirus-host interactions. The primary research focus of our laboratory is to study the host innate immune response against retrovirus infection and our research is uncovering the molecular mechanisms of retroviral restriction in non-human primates. Our ongoing research is characterizing the viral and host factors that drive selection, adaptation, and pathogenicity of chimeric SIV/HIV viruses (SHIVs) in macaque cells.

Qualifications: Bachelor's Degree in Biological Sciences or a related field. Previous laboratory experience is expected. Ability to work independently with excellent organizational and time management skills.

Summary of Duties: The research technician is expected to:

§ Assist in performance of biomedical research projects.

§ Carry out experimental designs for research projects and perform routine experiments.

§ Help evaluate, interpret and assess experimental data and quality control of assays.

§ Record and consolidate research data.

§ Maintain databases, order supplies and maintain inventories.

 

Required Skills:

§ Experience with cloning, cell culture and basic molecular biology techniques desired.

§ Ability to use Microsoft Office programs required.

§ Understanding of general and specific laboratory procedures, and scientific approach and methodologies.

§ Ability to follow research methodology and protocol.

§ Ability to read, understand, follow and enforce safety procedures.

§ Strong critical thinking and attentiveness to detail required.

This position would be ideal for recent or soon-to-be graduates who are interested in gaining research experience over two years before starting graduate or medical school. Two year (or more) commitment strongly preferred.

Interested candidates should submit:

1. A cover letter expressing their interest in biomedical research and future career goals

2. CV

3. Contact information for three references

Application materials and questions regarding the position should be sent to Dr. Amit Sharma: sharma.157@osu.edu

Amit Sharma, PhD Assistant Professor Department of Veterinary Biosciences Department of Microbial Infection and Immunity 366 VMAB, 1900 Coffey Road Columbus, Ohio 43210 Email: sharma.157@osu.edu

Posted March 27, 2019

 

 

Full Time Research Assistant, Hormoz Lab at Harvard Medical School and Dana-Farber Cancer Institute

Overview: Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The Hormoz Lab at Harvard Medical School and Dana-Farber Cancer Institute (https://hormoz.hms.harvard.edu/) seeks a highly motivated and dedicated full-time Research Assistant.  Hormoz lab studies the behavior of individual cells during development and in diseases such as cancer. Your project would involve analyzing expression levels of thousands of genes in individual bone marrow cells obtained from patients with certain types of chronic myeloid leukemias (called myeloproliferative neoplasms). We will work with clinicians at the Dana-Farber Cancer Institute to obtain the cells from the patients and use single-cell sequencing to read out expression levels of thousands of genes in each cell. Your task would be to distinguish the malignant cells that carry the cancer mutation from the healthy cells and identify the disease-initiating cell (the culprit) in each patient. You would then relate the identity of the disease-initiating cell to how the disease manifests in each individual patient. Ultimately, the aim would be to identify personalized targeted treatments that will preferentially eradicate the malignant cells in each patient.

Responsibilities: Commonly performed tasks will include tissue culture, DNA cloning, DNA editing with CRISPR/Cas9, FACS analysis, RNA extraction, real time PCR, sequencing, and different forms of microscopy. Accordingly, prior experience in molecular biology, cell biology or mammalian cell culture is helpful but not required; computational expertise and experience in coding will also be very helpful. The successful applicant will be eligible for authorship on resulting publications, including lead authorship where appropriate, and will acquire critical experience in applying cutting-edge techniques in biology to directly helping patients. This is an exciting opportunity and great preparation for anyone considering continuing on to MD, PhD, or MD-PhD programs.

Qualifications The successful candidate will be enthusiastic, self-motivated, dedicated, possess excellent organizational skills, be attentive to detail, and capable of forming effective working relationships with members of the research team. A BA/BS or equivalent in Biology, or a related field is required. Experience working with mammalian cell culture and the corresponding molecular biology, genomics, and cloning techniques is highly desirable.

To apply, please send your CV to sahand_hormoz@hms.harvard.edu

Posted March 27, 2019

 

 

PostBac opportunity in programming cellular function, Church Lab, HMS

Dr. George Church, Genetics, gchurch@genetics.med.harvard.edu , NRB238, http://arep.med.harvard.edu

Description: While all living cells actively control and fluctuate the expression level of thousands of genes in response to time and environment, in biological research we primarily use constitutive (always on) promoters. The benefit of specifying gene expression temporally in cells goes beyond simply growing populations of cells that blink different colors. It is also one of the necessary components towards programming sequential temporal behavior into living cells - one of the key requirements for functional living computers.

https://www.addgene.org/tetracycline/

https://www.nature.com/articles/nmeth.3147

Skills required: Molecular biology lab coursework required. Prior experience in plasmid construction and primer design strongly preferred.

Learning outcome: Molecular biology laboratory skills, genome editing experience, microscopy experience, experimental design, data analysis method, presentations

Expected work and length: Summer: Full time (35 hours/week), possible to extend through Fall/Spring contingent on performance

Mentoring: Work will take place at Harvard Medical School’s NRB building with close mentorship from senior graduate student within an active team of other post docs. Mentorship meetings can take place from daily to weekly based on need.

Position is funded through a lab grant, but would be happy to support student in applying for scholarship/fellowships for experience.

Email a cover letter and resume to George Chao at gchao@mit.edu

Posted March 27, 2019

 

 

Laboratory research coordinator, Georgetown University

The upcoming SAMP Lab (Sensory and motor plasticity, PI: Ella Striem-Amit) at Georgetown University (Washington DC, USA) is looking for a full-time laboratory research coordinator starting in September 2019.

We examine the balance between innate brain organization and experience-dependent plasticity by studying people with sensory and motor deprivation (e.g., blindness, dysmelia) using behavioral and fMRI techniques.

The Laboratory Research Coordinator will work on projects involving fMRI and behavioral testing of sensorimotor and visual processing, as well as perform administrative duties.

The position is particularly suited for a recent graduate from a Neuroscience, Psychology, Cognitive Science, Computer Science or related undergraduate program who is seeking to work in an innovative research environment in preparation for graduate school.

The primary duties and responsibilities of this position include:

  • Running Experiments for the lab: Recruit and interact with study participants and run experiments in the lab (behavioral, fMRI), as well as online behavioral experiments (e.g. Amazon Mechanical Turk). Administrative responsibilities associated with these experiments, including maintaining lab records, participant reimbursements, uploading and organizing data, and managing IRB documentation and reviews.
  • Maintaining Infrastructure: Responsibility for purchasing and maintaining lab equipment and managing data storage, including fMRI equipment, lab computers, and lab accounts on software and storage services.
  • Research Projects: Responsibility for carrying out independent research projects and assistance with the research projects of students and postdocs. These projects will involve a combination of behavior and fMRI of actions in special populations. The laboratory research coordinator will be expected to participate in all aspects of experiment design, analysis, and communication, including creating stimuli and experimental protocols, collecting and analyzing data, writing up results for publication, and presenting findings at conferences.
  • Additional administrative duties: Interaction with outside vendors, maintenance of laboratory records and website, assistance with coordinating lab meetings, conference trips and visits, assistance in writing grant applications and reports.

Position duration: At least two years of commitment is required.

Requirements:

BA/BS in Neuroscience, Psychology, Cognitive Science, Computer Science or related scientific field

Experience with scientific computing (Matlab, Python, or R)

An ability to solve technical problems independently

Strong organizational skills

Ability to work well with others

Some prior research experience (experience with fMRI analyses an advantage)

To learn more or apply for this position, please email your CV to Ella Striem-Amit (striemamit@fas.harvard.edu) with the subject line: Lab research coordinator position.

Georgetown University is an Equal Opportunity/Affirmative Action Employer fully dedicated to achieving a diverse faculty and staff.  All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, national origin, age, sex, disability status, protected veteran status, or any other characteristic protected by law.

Posted March 19, 2019

 

Research Assistant, Wainger lab, MGH

waingerlab.org

We are a young and vibrant group applying biological, physiological and computational tools to understand and identify new treatments for motor and sensory neuron diseases. The laboratory is seeking a motivated and enthusiastic research assistant with experience in molecular biology and in particular stem cell biology to support preclinical studies related to Amyotrophic Lateral Sclerosis (Lou Gehrig’s Disease) and pain. The research technician will contribute to the intellectual development of a project, attend and present at lab meetings, and engage in the scientific community through opportunities to attend conferences and publish papers. The major responsibilities will include stem cell culture and differentiation, analysis of molecular disease-related phenotypes using patient and control as well as gene-edited iPSC lines, quantitative analysis of expression and sequence data, general molecular biology techniques such as immunohistochemistry, RNA isolation and PCR to analyze the cells of interest. Additional work will include assistance with ordering, laboratory maintenance and animal husbandry. The candidate must be able to make a two-year commitment.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

  • Stem cell culture and differentiation
  • High-content imaging and physiology (calcium imaging/ optogenetics)
  • Bioinformatic analysis of expression and sequence data
  • Mouse brain and spinal cord dissection
  • Purification of RNA and PCR
  • Perform task associated with ordering, animal husbandry, and lab uptake
  • May assist with training other personnel

SKILLS/ABILITIES/COMPETENCIES REQUIRED: Must be an enthusiastic, diligent and professional team player with excellent time management skills. Meticulous detail about laboratory techniques and documentation are required, as are the ability to work independently and as a member of a team. The candidate must possess excellent verbal and written communication skills. The position requires accurately maintaining records of laboratory work in sufficient detail for reproduction of the experiments, organizing, analyzing and summarizing acquired data. The candidate may assist with drafting or contributing to the preparation of research papers, manuscripts or other documents for publication and/or presentation.

EDUCATION:  BA/BS in neurobiology, developmental biology, molecular biology or related field

EXPERIENCE:  One year of previous relevant laboratory work experience strongly desired.

PLEASE CONTACT AND INCLUDE COVER LETTER, CV, AND TRANSCRIPT:  brian.wainger@mgh.harvard.edu

 

Posted March 8, 2019

 

Research Assistant, Lehtinen Lab, Boston Children's Hospital

The Lehtinen lab is looking for a motivated research assistant to join our team in the vibrant Neuroscience research community of Boston Children’s Hospital and Harvard Medical School. We are fascinated by how the choroid plexus - cerebrospinal fluid system actively instructs mammalian brain development and life-long health. The position includes working collaboratively with lab members on all aspects of research using techniques spanning molecular and cell biology, to calcium imaging in awake mice. On-going projects include, but are not limited to, (1) maternal-fetal environment, (2) mental health, (3) hydrocephalus, (4) brain barrier functions, (5) brain therapeutics. An important second aspect of the position entails helping with rodent husbandry as well as routine lab maintenance (These aspects of the position are shared among several individuals). There is the possibility to develop an independent research project, if desired. A background in Neuroscience is strongly recommended. We ask for a minimum 2-year commitment, with a projected start date in June 2019.

Check out our lab webpage to see more about life in the lab:  http://www.childrenshospital.org/LehtinenLab

Interested applicants should contact Maria by email at:  maria.lehtinen@childrens.harvard.edu

Please include a few sentences describing of your background and research interests, and a copy of your CV.

posted March 8, 2019

 

 

Clinical Research Coordinator, The Program in Nutritional Metabolism, MGH

Opportunity Description: The Program in Nutritional Metabolism (PINM), a clinical research group at Massachusetts General Hospital, is seeking highly motivated college graduates for a two-year position as a Clinical Research Coordinator (CRC). PINM specializes in advancing our knowledge of the complex interplay between cardiovascular disease, the gastrointestinal system, metabolic disorders, and HIV infection. For example, people who have HIV are twice as likely to develop heart disease during the course of their lifetime. Through the conduct and analysis of clinical trials at MGH, PINM researchers have made major contributions to our understanding of this phenomenon.

CRCs at PINM thus have the opportunity to work on clinical research that is rewarding and has far-reaching implications. Working as a part of a team, CRCs are responsible for facilitating the long-term success of a research trial in several ways. These include:

  • Conducting patient visits at the MGH Clinical Research Center and other hospital sites
  • Facilitating the screening and recruitment of new patients
  • Collecting and managing data
  • Performing structured patient interviews
  • Ensuring compliance with various regulatory bodies such as the MGH Institutional Review Board

Hardworking and ambitious coordinators may also have the chance to contribute to the preparation of manuscripts for authorship/publication.

This position is ideal for a diligent pre-medical graduate who is looking to gain significant research experience in a clinical setting before enrolling in medical school. CRCs at PINM have a high degree of responsibility. The ability to prioritize tasks is important. The successful candidate will also demonstrate a meticulous attention to detail and strong interpersonal skills. A background in research/clinical settings is desirable but not required.

This is a paid position. CRCs will work 40 hours per week. CRCs will likely be expected to start in late May or early June.

How to Apply: To apply for this position, please contact Drs. Steven K. Grinspoon (sgrinspoon@mgh.harvard.edu) and Suman Srinivasa (ssrinivasa@mgh.harvard.edu) with a resume and a cover letter. Applicants will be considered on a rolling basis.

Posted Feb 21, 2019

 

 

Biomedical Research Assistant, Rockefeller University

We are currently hiring graduating seniors for 1-2 year biomedical research assistant positions to work closely with senior scientists and participate in challenging, complex, and dynamic research projects.

As a Rockefeller research assistant, you will:

  • Conduct cutting-edge biomedical research
  • Interact with senior scientists who are committed to your mentorship
  • Learn advanced lab techniques and build strong analytical skills
  • Present your work at lab meetings, journal clubs, and conferences
  • Attend a rich program of scientific meetings, lectures, and special events
  • Enjoy excellent compensation and benefits, including tuition reimbursement
  • Unspoken luxuries also include our intimate community, extreme prestige (number of Nobel prizes and laureates on-campus), incredible funding and core facilities, and the perks – free beer at our Faculty Club, state-of-the-art gym facility, river view, living in NYC!

A smart first step before grad school: After a two year period, research assistants go on to the top Ph.D., M.D. and MD/Ph.D. programs, while some choose to continue on as a third year researcher to learn more.

Personalized recruitment: When you apply, we learn about your goals, educational background, research experience, and scientific interests to find you a position you’ll thrive in.

Requirements: Bachelor's in science required. Will consider Master’s degree. Previous laboratory experience preferred.

Our Culture:

  • incredible haven for some of the best science in the world
  • scientific oasis
  • inspiring, collaborative atmosphere
  • strong social and environmental consciousness
  • intellectually curious academic environment
  • 14-acre campus setting in NYC

Follow your passion for excellence in science and join our researchers in the pursuit of science for the benefit of humanity.

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veteran

Kara Marshak | Assistant Director of Talent | Human Resources

The Rockefeller University | 1230 York Avenue | New York, NY 10065

Telephone 212.327.8300 | Fax 212.327.8699

Posted Feb 7, 2019

 

 

Clinical Research Assistant, The Movement Disorder Center, Beth Israel Deaconess Medical Center

The Movement Disorder Center at the Beth Israel Deaconess Medical Center, a Parkinson’s Foundation Center of Excellence and a Huntington’s disease Society of America Center of Excellence

The Clinical Research Assistant will work on clinical research projects studying medical and surgical treatment of neurological disorders including Parkinson's disease, dystonia, and essential tremor. Research responsibilities include: scheduling research subjects, preparing charts and lab supplies for subject visits, filing documentation related to research studies, recording research data on source documents and electronic databases, collecting and processing laboratory specimens, administering patient questionnaires, and assisting in patient recruitment. 

Administrative and other responsibilities include assisting with the completion of regulatory and Institutional Review Board documents, organizing logistics for center events, booking room reservations for center meetings, and assembling patient information folders. The CRA also will also assist with tasks related to the center’s wellness and educational programs. As a member of the interdisciplinary team, the CRA will be expected to attend team meetings and educational seminars, which may occasionally happen on weekends.

Interested applicants are asked to commit to flexible volunteering hours during the 2019 spring semester if possible, and transition into the full-time paid position after graduation in May of 2019, contingent on satisfactory performance during the volunteer period. The candidate must be willing to commit to the full-time CRA position, starting after graduation toward the end of May or the beginning of June, for two years.

Applicants should have a Bachelor's Degree in a health/science field (after graduation in May 2019), excellent organizational skills, computer literacy, an interest in clinical research, and the ability to function independently.  Good interpersonal skills are essential.

Interested candidates should please contact Elizabeth Morrison at:  emorris4@bidmc.harvard.edu        

Posted Jan 28, 2019

 

 

Clinical Research Assistant, Neurological Disorders, Beth Israel Deaconess Medical Center

Gait Analysis in Neurological Disease and Deep Brain Stimulation Coordinator

The Clinical Research Assistant will work on clinical research projects studying medical and surgical treatments of neurological disorders including Parkinson’s disease.

Main Project 1: Gait Analysis in Neurological Disease

Research Responsibilities include: scheduling research subjects, coordinating study visits with study staff, collecting and processing the research data, administering patient questionnaires and exams, patient longitudinal follow-up, and maintaining compliance with all institutional and federal human research regulations.

Main Project 2: Deep Brain Stimulation Research Repository Database

Research Responsibilities include: consenting and enrolling all patients considering Deep Brain Stimulation at BIDMC, collecting and storing the research data on the database, administering patient questionnaires and exams. Additionally, CRA will assist department staff with managing the Deep Brain Stimulation Program and coordinating patient visits.

Administrative and other responsibilities include: assisting with the completion of regulatory and Institutional Review Board documents, assisting with manuscript preparation and editing, training of study staff, and project management. The CRA will also assist with tasks related to the Department’s educational programs. As a member of the interdisciplinary team, the CRA will have access to multiple research and educational opportunities such as journal club, grand rounds, and research presentations. 

This position requires direct patient contact, so good interpersonal skills are essential. Applicants should have a Bachelor's Degree in a health/science field (after graduation in May 2019), excellent organizational skills, computer literacy, an interest in clinical research, and the ability to function independently.

If you are interested in this position, please contact Dr VanderHorst by email (vvanderh@bidmc.harvard.edu) and enclose a letter of interest including career goals, CV, and the names, email address and phone numbers of 2-3 references.

Posted Jan 8, 2019

 

 

Wellness Works Assistant Coordinator, Beth Israel Deaconess Medical Center

The WellnessWorks Assistant Coordinator position oversees the daily operations of WellnessWorks, which is an umbrella program that provides exercise and educational opportunities for individuals with Parkinson’s Disease (PD) and their family members. Beth Israel Deaconess Medical Center has a well-renowned PD Center of Excellence. The center received a grant from the Parkinson’s Foundation in support of a program, “Calling All Artists”, which brings together artists with PD for education and support. There is a plan for expanding this program to the national and international level. The exercise programs under WellnessWorks include Rock Steady Boxing, Tai Chi, Yoga, PD Bootcamp, and PD Golf. Education and support programs include an orientation program, “Learn the Ropes”, a group for women with PD, and programs geared towards adult children whose parents have PD.

Responsibilities for this WellnessWorks Research Assistant position include regular communication with patients and instructors, in addition to maintaining enrollment, registration, and payment for the various above-described exercise programs and support groups. Participation in a multi-disciplinary team, designing flyers to market the programs, maintaining and analyzing systematized records of participant surveys, and assisting in the facilitation of a weekly off-site support group for care partners of individuals with PD are also aspects of this position. This position includes an opportunity to work collaboratively on publishing research relevant to the impact of wellness programs on health and wellbeing for the participants.

Qualified candidates will be able to be work creatively, independently, problem solve, advocate for patients, and multi-task, as well as having proficiency in Microsoft Excel, attention to detail, and exemplary interpersonal communication skills.

Interested applicants are asked to commit to flexible volunteering hours during the 2019 spring semester if possible, and transition into the full-time paid position after graduation in May of 2019, contingent on satisfactory performance during the volunteer period. The candidate must be willing to commit to the full-time RA position in July of 2019 for at least one year, but 2 (or more) years is preferred.

Interested candidates should please contact Elizabeth Morrison at:  emorris4@bidmc.harvard.edu        

 

Posted Jan 28, 2019

 

 

Laboratory Research Assistant, Beth Israel Deaconess Medical Center

This laboratory research position is available in the spring of 2019 or sooner (with some flexibility in the start date) in the laboratory of Dr. David K. Simon at Beth Israel Deaconess Medical Center and Harvard Medical School. The Research Assistant will work closely with others in the lab on translational research relating to pathophysiology and neuroprotection in Parkinson’s disease.  RA responsibilities will include helping with tissue culture experiments, handling mouse colonies, DNA and RNA isolation, genotyping, cloning, sequencing, cryostat sectioning of mouse brain tissue, immunohistochemistry, quantitative PCR, western blots, and other methods.

Some laboratory experience with tissue culture and with mouse handling is helpful but not required. Instruction will be provided for required techniques as needed.

A 2 year (or more) commitment is preferred. The Laboratory Research Assistant is expected to earn co-authorship on publications. There are ample opportunities for educational activities, including weekly lab meetings, journal clubs, video conferences, neurology grand rounds, and others.

Interested candidates should contact Dr. Simon by email (dsimon1@bidmc.harvard.edu). Please include a CV and contact information for two or more people who can serve as references.

 

Posted Jan 28, 2019

 

Laboratory Research Assistant I, Beth Israel Deaconess Medical Center

A Laboratory Research Assistant position will become available in May 2019 in the Laboratory of Dr Veronique VanderHorst at Beth Israel Deaconess Medical Center and Harvard Medical School. The Research assistant will be working as part of a team on subcortical neural circuits involved in gait. These circuitries are being studied in postmortem tissues of older subjects with neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease and of healthy aging subjects.

Responsibilities will involves specimen preparation, tissue processing (sectioning, immunohistochemical staining, digital scanning), state of the art image processing, semi-quantitative analysis of markers in human tissues, and data management. The Research Assistant will work with senior staff in the lab to develop new protocols, and is expected to communicate effectively with off-site lab staff providing the tissues and statisticians who will receive the data generated.

The Laboratory Research Assistant will be trained by experienced staff and is encouraged to contribute to publications. The candidate will have the unique opportunity to learn from clinical, translational as well as basic science projects conducted by others in the lab as well as through educational activities that include weekly lab meetings, Systems Neuroscience Seminars and others.

The appointment is for a minimum of 1 year with the possibility to extend.

This position requires a Bachelor's Degree in a science field (after graduation in May 2019), a strong team spirit, excellent organizational and analytical skills, attention to detail, proficiency in Excel, and the ability to function independently. Image analysis or lab experience is preferred but not necessary. Excellent communication skills are necessary to between

If you are interested in this position, please contact Dr. VanderHorst by email (vvanderh@bidmc.harvard.edu) and enclose a letter of interest including career goals, CV, and the names, email address and phone numbers of 2-3 references.

 

Posted, Jan 28, 2019

 

Clinical Research Coordinator II, Massachusetts General Hospital
Job Code: 000058   Grade: 014  FLSA Status: exempt
Department/ Unit/Section: Health Decision Sciences Center, General Medicine Div.
Reports To: Karen Sepucha, PhD

This is an exciting opportunity for an entry- to mid-level research assistant who is interested in working on shared decision making and patient-centered research projects. Under the supervision of the Project Manager and Director and according to established policies, procedures, and detailed instructions, the incumbent will serve as Clinical Research Coordinator (CRC) within the Health Decision Sciences Center (HDSC). This position is funded through several external grants including the Donaghue Foundation, CRICO, and Patient Centered Outcomes Research Institute (PCORI).

The CRC will be involved in activities supporting research studies on shared decision making. The Donaghue Foundation grant is a large study measuring the quality of surgical decisions across the Partners HealthCare System for patients with hip and knee osteoarthritis, spinal stenosis and herniated disc. The CRICO grant takes the Donaghue grant a step further and also examines trust and regret among patients in their medical care team, postoperatively. The PCORI funded study is a comparative effectiveness study of different training interventions to enhance the quality of conversations between doctors and patients about colon cancer screening.

To support these studies, the CRC will be responsible for screening patients for eligibility using the electronic medical record, administering surveys, entering study data into a database, following up with study participants by phone, identifying and handling issues with recruitment and retention, preparing study progress reports and presentations, and serving as a liaison to collaborators within MGH and across organizations. This position will provide support to higher-level administrative and project staff in the HDSC. In this multi-faceted role, the candidate will also perform administrative duties such as schedule appointments and meetings, process check requests, prepare survey mailings and coordinate conference calls and meetings for the team. The candidate must demonstrate superior organizational, administrative, time management, and communication skills, as well as intellectual independence and initiative. The ability to work both independently and as part of a team is essential. He or she must maintain professionalism at all times. Other job duties and responsibilities are listed in detail below.

 

General research duties: The Clinical Research Coordinator (CRC) will be responsible for assisting in the broad array of research and administrative responsibilities required to conduct research. The CRC will conduct literature searches and generate summaries for use in grants, abstracts, and manuscripts; maintain bibliographic reference lists for grants and manuscripts; screen and recruit study subjects and maintain enrollment reports; prepare study mailings and reminders; conduct chart reviews; conduct data entry and quality checks on data entry; maintain human subjects committee documentation and assist with preparation of amendments and continuing reviews; and coordinate research study meetings among collaborators, and assist with ongoing projects as needed. Further, the CRC may have the opportunity to assist in writing research papers based on his or her skills and developing interests within the various projects.

Specific duties: The CRC’s responsibilities include assisting the HDSC Director (Karen Sepucha, PhD) and the HDSC project manager. The goal of the Donaghue Foundation grant is to examine whether routine measurement of shared decision making for elective surgery decisions, with feedback on performance to clinicians and administrators, has the potential to improve the quality and value of care provided to patients. The study just finished year 1 study activities collecting patient and clinician baseline data and is currently in year 2 of the study activities where study staff will engage clinicians, patients and administrators to explore how the baseline data may be used to design incentives to promote SDM and increase value.

The CRICO and PCORI grants will begin study activities this spring and involve medical chart review to confirm patient eligibility, preparing and sending survey packets (e.g. cover letters, questionnaires, mailers) for large mailings to patients, maintaining a database of mailings and reminders, and entering survey data into the databases. The CRC will also troubleshoot recruitment and enrollment issues, and assist with data entry and preliminary analyses. The CRC will maintain IRB documentation, assist with preparing amendments and continuing review documentation as needed.

Additionally, the CRC will assist with ongoing research and other HDSC shared decision making project work as appropriate.

Administrative duties: The Clinical Research Coordinator will also assist with administrative support for the Center. The CRC will help schedule meetings and coordinate conference calls, take notes for meetings, prepare and submit check requests and expense reports, order food and reserve rooms for meetings, and other paperwork that may need to be processed.

Performs general word processing: Duties will include letters, memos, manuscripts, grants, case study reports, and other types of correspondence.

Other duties:

• Provides administrative support and tracking of research project progress, as well as preparing routine reports to funders and leadership.

• Maintains research-related office files and record keeping procedures.

• Attend team meetings and project meetings and conference calls, prepare minutes of meetings when applicable. Some meetings may be held after normal business hours.

• Assist with creation, production and distribution of the promotional materials and communication tools (i.e. brochures, newsletters, and annual reports).

• Prepare PowerPoint presentations when applicable.

• Work with staff to meet grant deadlines for all new and competing grants, helping with typing, pagination, copying, references, etc.

• Experience with Microsoft Word, Access, Excel, Power Point and Outlook

• Assist with use of Reference Manager software (or EndNote) to perform literature searches using PubMed and other search engines, and perform Internet searches using MS Internet Explorer and various search engines.

• Experience with statistical software such as SAS, SPSS or Stata preferred

Performs all other duties or special projects that are unit/center specific and that are appropriate for this level.

QUALIFICATIONS: Bachelors degree required, MPH or Masters degree preferred. 1 or more years of relevant job experience in health care, research or related field is preferred

Experience or relevant coursework in healthcare policy, shared decision making, survey research, and/or healthcare quality improvement is preferred

SKILLS/ ABILITIES/ COMPETENCIES REQUIRED:

• Experience with common PC computer software including Microsoft Word, PowerPoint, Excel, Access and Outlook. Typing speed of 50+ wpm.

• Excellent communication and writing skills.

• Superb proofreading skills.

• Ability to work well both independently and collaboratively as part of a research team.

• Ability and willingness to learn new research and administrative skills.

• Time management: Exceptional organizational skills and ability to organize time and priorities effectively, asking for direction when appropriate. Flexibility to handle multiple tasks and deadline pressures.

WORKING CONDITIONS: Describe the conditions in which the work is performed.

Normal office conditions. You will be provided with a carrel and a Partners standard computer. As part of the position, the CRC will occasionally be required to attend meetings outside of regularly scheduled hours.

Contact: Felisha Marques, MPH, CCRP  Senior Clinical Research Coordinator
Health Decision Sciences Center  Massachusetts General Hospital
100 Cambridge Street, Suite 1600  Boston, MA 02114
(T) 617.724.3295  Email: fmarques@partners.org   https://mghdecisionsciences.org/

Posted Jan 28, 2019

 

 

Staff Research Associate (SRA)/Specialist, UCSF 

We are recruiting a Staff Research Associate (SRA)/Specialist to assist with ongoing multidisciplinary cellular engineering projects. Our lab has pioneered the application of novel genetic engineering technologies such as CRISPR to primary human immune cells (Schumann et al., PNAS 2015). These new technical abilities have furthered our labs research into the genetic underpinnings of autoimmune disease and T cell biology (Farh and Marson et al., Nature 2015), as well as opened the door to novel cancer immunotherapies based on engineered human immune cells (Roth et al., Nature 2018). In addition to cell editing, our lab integrates genomic analysis (e.g. ChIP-seq, ATAC-seq, RNA-seq), human disease genetics, and high dimensional screening approaches for in vitro and in vivo studies of T cell function (Simeonov et al. Nature 2017; Shifrut and Carnevale et al. Cell 2018).

Working as part of a multidisciplinary group, the SRA will utilize various protocols to generate the molecular components, such as DNA constructs, necessary for specific cellular engineering experiments. Additional responsibilities will consist of isolation and culture of primary human immune cells, as well as functional analysis of engineered cells via Sanger sequencing, next-generation DNA sequencing, and flow cytometry. Strong organizational and communication skills are required. For exceptionally skilled applicants, opportunity exists to extend the SRA’s role to include the design and completion of cellular editing experiments, as well as in vivo analysis of novel cellular cancer immunotherapies. This position represents an excellent opportunity to gain exposure to basic laboratory skills as well as genetics and genome engineering skills in a dynamic, well-established research environment.

Required Qualifications:

• BA/BS degree and one or more years of laboratory experience utilizing techniques or methods required by the position; or an equivalent combination of education and experience
• Experience with general laboratory techniques, especially basic molecular and cellular biology techniques (including but not limited to DNA and RNA isolation, PCR, gel electrophoresis, DNA assembly, bacterial transformation, mammalian cell culture, etc.)
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities
• Ability to work independently and as a member of a research team
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines

Preferred Qualifications

• Prior experience with DNA sequencing technologies, including Sanger and NGS
• Prior experience in the design and assembly of DNA constructs (via restriction digestion and ligation, Gibson assemblies, Golden-Gate assemblies, etc.)

• Prior hands on experience with mouse handling and injections

Payment is according to the UCSF pay scale. UCSF is an equal opportunity/affirmative action employer. All qualified candidates are encouraged to apply. Please submit your complete application documents including CV and references to: Theodore.roth@ucsf.edu and Alexander.marson@ucsf.edu

Alexander Marson, M.D., Ph.D. 513 Parnassus Avenue
Assistant Professor, Department of Microbiology and Immunology Room HSW 1053
Department of Medicine & UCSF Diabetes Center alexander.marson@ucsf.edu
Member, Innovative Genomics Initiative (IGI) http://marsonlab.ucsf.edu

Associate Member, UCSF Helen Diller Cancer Center (415) 502 2611

Posted Jan 28, 2019

 

Available starting Spring 2019: Two full-time, twoyear Neurobiology Research Assistant positions, Boston Children's Hospital

We are looking for two talented and motivated research assistants to join Dr. Mustafa Sahin’s laboratory in the Neurology Department at the Boston Children’s Hospital - a Harvard Medical School affiliated teaching hospital.

You will be working with a research team that is focused on elucidating the cellular and molecular underpinnings of Tuberous Sclerosis Complex (TSC), a rare genetic neurodevelopmental disease, using behavioral, physiological, and molecular techniques. One area you would be working in is the characterization of EEG signatures from various mouse models of autism spectrum disorders and epilepsy. There are opportunities to learn and perform rodent surgeries for implanting EEG devices, work with pharmaceutical companies, design longitudinal mouse drug studies, and work with tissue cultures. Research assistants will also be responsible for lab managerial tasks and mouse husbandry.

We are looking for individuals who are self-motivated and have strong organizational, management and laboratory skills who will be comfortable handling mice. This position is a great stepping-stone towards further graduate training in various professions in the medical field and would be best suited for students with prior backgrounds in biological sciences or neuroscience. Minimum requirements include completion of a bachelor's degree in neuroscience, biology, chemistry, or a closely related field, and some lab experience. We encourage applicants with experience handling or breeding rodents, rodent surgery, tissue culture, biochemical assays, or genotyping to apply.

The selected applicants will begin in Spring 2019 or earlier (earlier start dates are encouraged). This is a two year, full-time, salaried position with affordable health, vision and dental insurance, generous levels of time off, 403(b) retirement savings plan, pension, tuition reimbursement, cell phone plan discounts, and discounted rates on T-passes (50% off).

If you are interested please email your resume and cover letter to the address listed below. Thank you and we look forward to hearing from you.

Sarika Gurnani  sarika.gurnani@childrens.harvard.edu  Research Assistant
Sahin Laboratory - Center for Life Science  Boston Children’s Hospital

Posted Jan 28, 2019