Research Position for a Graduating Senior, Involving Medical/Biological Imaging, Mathematical Biology, and Computer Science on a Joint Massachusetts General Hospital/Harvard University Project 1
A full-time research position will be available for a graduating senior interested in spending a year or two before continuing their education in medical or graduate school, as well as for individuals with somewhat more experience, including students with Masters Degrees. Previous holders of this type of position have had the opportunity to work on research projects and to publish scientific papers on their work, and many individuals have published first-authored papers on their work. For students with an interest in medicine, exposure to clinical medicine is encouraged. The work of our group has concerned: the assembly of data, and the development of improved mathematical methods, for predicting the outcome for cancer patients; the assembly of data, and the development of improved mathematical methods, for understanding and assessing the growth of fetus and children; the identification of screening schedules for reaching the maximal possible reduction in cancer death achievable by cancer screening; the application of modern computer speech and telephony for developing scheduling/reminder systems for increasing the use of preventative medical interventions such as mammography and influenza immunization. The program is a collaborative project between individuals at the Massachusetts General Hospital, Harvard, and MIT, and is located on the Harvard Campus in Cambridge.
The position involves the development of improved cancer specimen and biological imaging technologies, especially micro x-ray tomography, the mathematical analysis of biological growth, and the use of mathematical methods to examine the medico-legal consequences of delay in the treatment of cancer. The work will involve improvement and use of 3D image analysis, with advanced software tools (3D Studio MAX, Matlab Image Analysis Software Toolkits, 3D Slicer, ITKSNAP, etc.). Students with training in computer science and/or mathematics, or computer animation, who also have interests in biology and/or medicine, are encouraged to apply.
The target date for employment is June-August 2017, but there are also opportunities for individuals who wish to being now, or participate part time now in a trial capacity, or carry out research projects this semester.
Please reply by email with CV or resume to:
James S. Michaelson Ph.D., Director, Laboratory for Quantitative Medicine, Massachusetts General Hospital; Department of Pathology, Harvard Medical School; Departments of Pathology and Surgery, Massachusetts General Hospital
Email: JamesMichaelsonPhD@gmail.com, http://www.lifemath.net/
Posted March 20, 2017
Research Technician, Richard Sherwood Lab, Division of Genetics, Brigham and Women's Hospital
We are seeking outstanding candidates for a research technician position in the lab of Richard Sherwood (http://sherwoodlab.bwh.harvard.edu/) in the Division of Genetics at Brigham and Women’s Hospital/Harvard Medical School. Our lab uses advanced CRISPR/Cas9 genome editing and genomic screening techniques to understand how transcription factors dictate cell fate. Our eventual goal is to build computationally predictive models of cell differentiation that would enable us to turn stem cells into therapeutically relevant cell types including pancreatic beta cells and intestinal cell types. We have invented several high-throughput genome editing assays that we are now applying to this goal, and we collaborate closely with David Gifford’s computational lab at MIT to build computational algorithms that predict stem cell activity.
The research technician position would involve stem cell culture, genome editing, genomic analysis, and molecular biology. A strong biology background and prior lab experience are required but not necessarily in the techniques mentioned above. Previously trained technicians have co-authored journal articles and moved on to MD/PhD programs, so we are looking for someone who could commit 2 years to an exciting research position to prepare them for graduate/medical school. To apply, send a cover letter, CV, and names and contact information for two references to email@example.com.
BWH & HMS are affirmative action/equal opportunity employers.
Posted March 3, 2017
Research Assistant/Technician, New England College of Optometry
Applications for a full-time grant funded Research Assistant/Technician are being accepted by the New England College of Optometry for work in Dr. Debora L. Nickla’s lab. The NIH-funded experiments will study various parameters of the circadian rhythms in axial length and choroidal thickness using the chick model of myopia. The PI is collaborating with two colleagues at The University of Pennsylvania and Emory University, where molecular analyses on tissues will be carried out by two investigators.
Applicants should hold a BS or MS in biology and have experience in animal research. Experience in the harvesting of tissues for molecular analyses is desirable. He/she will be expected to participate in circadian experiments 1-2 times per month, which will involve round-the-clock measurements, or ocular tissue collection.
The New England College of Optometry (NECO) is a professional graduate school in Boston’s Back Bay with plentiful scientific and cultural resources. The Myopia Research Center at NECO is a strong group of scientists covering various aspects of myopia development. Salary is commensurate with experience and this is a benefits eligible position. Interested candidates should send a cover letter and C.V. to HRDepartment@neco.edu.
The College is an Equal Opportunity employer and encourages all qualified candidates to apply.
For more information about employment, visit Employment Opportunities. Posted Feb 23, 2017
Description: The Dominic Walsh laboratory at the Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School is accepting applications for a technical research assistant 1 (TRA1) to work on an exciting new project focused on the role of extracellular vesicles in neurodegenerative disease. Working under the general supervision of the Principal Investigator, the successful candidate will interact on a day-to-day basis with a team of talented postdoctoral research fellows to study the roles of extracellular vesicles in cell-to-cell transfer of neurotoxic protein assemblies. The candidate will conduct a variety of cellular and biochemical experiments with clearly established methodologies, including but not limited to: i) neural cell line, primary neural and induced neuron culture, ii) mechanical, chemical and immuno-isolation of extracellular vesicles from biological fluids, and iii) protein assays, including ELISA and western blot. In addition, the applicant will be expected to perform basic data analysis relevant to the aforementioned methodologies.
Requirements: Bachelor’s degree in biochemistry, neuroscience, cell biology or a related biomedical subject. The successful candidate should also have at least 1 year experience in a laboratory setting and familiarity with basic biochemical methodologies. Experience with cell culture, protein assays and chromatography is preferred.
Contact: Expressions of interest should be directed to Grant Corbett (firstname.lastname@example.org). Please include “Technical Research Assistant I” in the email title.
Principal Investigator: Dominic M. Walsh. Ph.D. - Lab Website
Availability: Immediate. Posted Feb 20, 2017
Research Assistant, Dr. Kevin Hughes laboratory, MGH Surgical Oncology
The Hughes lab at MGH is looking for a full time research assistant. This position will involve close collaboration with the BayesMendel group in the Biostatistics and Computational Biology Department at DFCI. The groups jointly work on a tool which provides absolute cancer risk predictions for various hereditary cancer susceptibility genes: http://ask2me.org/. The position will involve research in genetic epidemiology, cancer risk assessment, and health care management. In addition, the position will require work on databases of cancer patients at Partners hospitals. The work will concentrate on the development, data input and maintenance of specialized databases of family history and risk factors for cancer, as well as outcomes. He/she will use these specialized databases to analyze patient care and outcomes (involves sophisticated mathematical analysis of cancer outcome. They will also assist in managing IRB submissions, producing reports and the production of manuscripts.
Responsibilities and duties: While a research assistant is expected to contribute in many ways to the research projects, typical responsibilities include the following: literature reviews; Collect and analyze data; Prepare materials for submission to granting agencies and foundations; Maintain accurate records of interviews, safeguarding the confidentiality of subjects, as necessary; Summarize interviews; Provide ready access to all experimental data for the faculty researcher and/or supervisor; Manage and respond to project related email; Prepare, maintain, and update website materials; Attend project meetings; Attend area seminars and other meetings as necessary; Summarize project results; Prepare progress reports for the PI; Prepare other articles, reports, and presentations.
Qualifications: Bachelors Degree in biology, healthcare, or a related field is preferred. Background in genetic epidemiology and big data experience is ideal.
- Strong analytical and problem solving skills, strong mathematical abilities, database knowledge, modelling.
- Strong written and verbal communication skills.
- Ability to collect and analyze data to assist in decision making.
- Ability to interact with people.
- Must be able to think creatively, often finding multiple solutions to a single problem.
- Strong PC skills required, knowledge of Microsoft Windows, Microsoft Office Suite, Powerpoint and Visio preferred, along with a willingness to learn new software
- Knowledge of databases.
- Ability to understand the work environment and competing and shifting priorities in conjunction with developing/meeting project and support goals.
- Ability to be flexible, versatile and adaptable in day-to-day activities.
- Must be able to communicate with laboratory staff through individual interviews and group discussions to gather information.
- Must be able to understand instructions and complete tasks both independently and as part of a team.
Position will report to Dr. Kevin Hughes, contact KSHUGHES@partners.org. Posted Feb 20, 2017
Data Manager Position, Lancet Global Health Commission on High Quality Health Systems (HQSS), Department of Global Health and Population, Harvard T.H. Chan School of Public Health
Description: The Lancet Global Health Commission on High Quality Health Systems in the SDG Era (HQSS Commission) is seeking to hire a talented Data Manager to oversee all core data management functions. Led by Dr. Margaret E. Kruk, the HQSS Commission is an applied research and evidence translation program dedicated to building the evidence base on the role of high quality health care in achieving global health goals. By managing the HQSS Commission data infrastructure, the Data Manager will help support research that strives to understand the quality of care in low and middle income countries that will contribute to health policy and system changes globally.
Background on the Lancet Global Health HQSS Commission: Guided by the values of originality, rigor, policy-relevance, transparency, and respect for local context and actors, the Commission will review current knowledge and produce new empirical work and policy recommendations on the level of quality in health systems today and the opportunity to save lives and reach the SDGs through higher quality health systems. It will build on and inform the work of other initiatives (e.g., Countdown 2030 Initiative, WHO’s quality work, IHI’s global quality efforts, etc.). All analyses will derive from existing publicly available data, such as Service Provision Assessments (SPA), Service Availability and Readiness Assessments (SARA), Service Delivery Indicators surveys (SDI); and Demographic and Health Surveys (DHS), etc.
The HQSS Commission aims to 1) define and describe the state of quality and responsiveness in the health systems of low- and middle-income countries, 2) propose tractable measures of quality, and 3) quantify the impact of quality enhancing strategies on reaching the SDGs. The work will be underpinned by an exploration of the ethical dimensions on quality, including the right to and equitable distribution of high quality health care.
Duties & Responsibilities: The Data Manager will have the overall responsibility for maintaining and directing the ongoing development of the data infrastructure that serves as the foundation for the HQSS Commission’s research. This individual will also function as the primary thought leader on the design of new data-related tools, training, and processes that could enhance HQSS Commission efforts.
Key functions include:
- Using a computer programming or statistical programming language (preferably Stata; Mata not required) for management of complex data
- Overseeing the maintenance of the HQSS Commission’s internal data infrastructure, including the maintenance data access rights and processes for data preparation, analysis and storage (e.g. standard file-naming conventions, program documentation, programming best practices, archiving of data from completed projects, etc.)
- Writing clear and replicable programs for data extraction, cleaning and management for use by the broader research group.
- Ensuring HQSS group compliance with all data security requirements and contractual agreements with nations and government agencies
- Preparing graphs, charts, and other visuals for the HQSS website, learning some web coding if necessary
- Preparing training materials on basic data cleaning and analyses for broader research group
- Developing strategic plans for the overall team’s IT and data resources to ensure that the team is well positioned to perform as efficiently and effectively as possible
This position is grant funded for one year from the date of hire.
Basic Qualifications: BA or BS and a minimum of 1 year of experience managing large-scale data projects for the purposes of supporting research or analysis. Experience in computer programming, particularly in one or several data management and statistical programming software packages (e.g., Stata, SAS, R), required. Exceptional organizational skills and attention to detail are necessary.
Additional Qualifications: Graduate degree in biostatistics or information science. The more experience dealing with large volumes of complex (multilevel) data the better. Stata experience is highly preferred. The ideal candidate will be highly productive working under pressure with time constraints, possess the ability to work independently, with supervision, or in collaboration as a team. Experience working in global health and with medical data is ideal, but not necessary.
Special instructions: In addition to a CV and resume, please send a code sample that reflects your programming capacity and experience with data management.
Contact: Please send your application to Daniel McKenna at email@example.com. Posted Feb 20, 2017
Staff Research Associate (SRA)/Specialist Position at the University of California, San Francisco
We are recruiting a Staff Research Associate (SRA)/Specialist to assist with ongoing multidisciplinary
cellular engineering projects. Our lab has pioneered the application of novel CRISPR genetic
engineering technologies to primary human immune cells (Schumann et al., PNAS 2015). These new
technical abilities have furthered our labs research into the genetic underpinnings of autoimmune
disease and T cell biology (Farh and Marson et al., Nature 2015), as well as opened the door to novel
diagnostic and therapeutic strategies based on engineered human immune cells. In addition to cell
editing, our lab integrates genomic analysis (e.g. ChIP-seq, ATAC-seq, RNA-seq), human disease
genetics, and in vitro and in vivo studies of T cell function.
Working as part of a multidisciplinary group, the SRA will utilize various protocols to generate the
molecular components, such as DNA constructs, necessary for specific cellular engineering
experiments. Additional responsibilities will consist of functional analysis of engineered cells via
Sanger sequencing, next-generation DNA sequencing, and flow cytometry. Strong organizational and
communication skills are required. For exceptionally skilled applicants, opportunity exists to extend the
SRA’s role to include isolation and culture of primary human immune cells, the design and completion
of cellular editing experiments, as well as functional genomics readouts following editing. This position
represents an excellent opportunity to gain exposure to basic laboratory skills as well as genetics and
genome engineering skills in a dynamic, well-established functional genomics research environment.
• BA/BS degree and one or more years of recent, directly related laboratory work experience
utilizing techniques or methods required by the position
• Experience with general laboratory techniques, especially basic molecular and cellular
biology techniques (including but not limited to DNA and RNA isolation, PCR, gel electrophoresis, DNA assembly, bacterial transformation, mammalian cell culture, etc.)
• Excellent organizational and interpersonal communication skills (verbal and written)
• Willingness and ability to learn new methods and skills for changing research priorities
• Ability to work independently and as a member of a research team
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines
• Prior experience with DNA sequencing technologies, including Sanger and NGS
• Prior experience in the design and assembly of DNA constructs (via restriction digestion
and ligation, Gibson assemblies, Golden-Gate assemblies, etc.)
Payment is according to the UCSF pay scale. UCSF is an equal opportunity/affirmative action employer. All qualified candidates are encouraged to apply. Please submit your complete application documents including CV and references to: Alexander.firstname.lastname@example.org. Posted: February 14, 2017
Research Technician, Harvard Medical School
I lead a group at Harvard Medical School focusing on CRISPR/Cas9 genome editing and stem cell biology, and I am looking for a research technician to work in my lab. Our lab uses advanced genome editing and genomic screening techniques to understand how transcription factors dictate cell fate. Our eventual goal is to build computationally predictive models of cell differentiation that would enable us to turn stem cells into therapeutically relevant cell types such as pancreatic beta cells. We have invented several high-throughput genome editing assays that we are now applying to this goal, and we collaborate closely with David Gifford’s computational lab at MIT to build computational algorithms that predict stem cell activity. The research technician position would involve stem cell culture, genome editing, genomic analysis, and molecular biology. A strong biology background and prior lab experience are required but not necessarily in the techniques mentioned above. I have previously trained several technicians who have moved on to MD/PhD programs, so I am looking for someone who could commit 2 years to an exciting research position to prepare them for graduate school. If interested, please email your resume to Rich Sherwood at email@example.com. Posted Feb 2017
McLean Hospital is a comprehensive psychiatric hospital committed to providing easy access to superior quality, cost-effective mental health services in the Boston area, Massachusetts and beyond. Since 1811, McLean Hospital has been a world leader in the treatment of mental illness and chemical dependency, research into the cause of mental illness and the training of generations of mental health care providers. McLean's multidisciplinary programs treat a broad range of psychiatric illnesses across the full continuum of care.
Working under the supervision of a Senior Research Assistant, Manager or Principal Investigator and following established policies and procedures, provides assistance on clinical research studies. May be responsible for the following activities: recruiting and evaluating patients for studies; collecting and organizing patient data; scheduling patients for study visits; performing clinical tests such as phlebotomy, EKG’s, etc; maintaining and updating data generated by the study.
Posted Feb 2, 2017
Research Associate in Dr. Feng Zhang's lab at the Broad Institute
The Zhang Lab at the Broad Institute of MIT and Harvard is looking for a highly-motivated individual to work as a full-time Research Associate within a highly creative and dynamic research team of scientists, engineers, and life science entrepreneurs. The individual will participate in research projects for a new faculty member. The laboratory uses a wide range of techniques including molecular, optical, computational, biochemical, electrophysiological and genetic approaches to develop and apply new technologies to the study of brain function and diseases and novel genome editing techniques.
Neuroscience Research Technicians, Neuroscience Institute at NYU Langone Medical Center
Post-Graduate Research Associate - Yale University
Post-graduate research associate in the Hoffman lab at the Yale Child Study Center (www.hoffmanlab.net) studying the genetics of autism spectrum disorders (ASD) using a zebrafish model system. The appointee will assist the principal investigator in multiple aspects of the research project. These include: 1. Genotyping zebrafish carrying mutations in genes that are strongly associated with autism spectrum disorders (ASD); 2. Performing phenotyping assays to identify abnormalities in brain development and behavior in zebrafish mutants of ASD risk genes; and 3. Conducting larval behavioral assays. The post-graduate associate will gain skills in molecular biology and genetics.
• Bachelor's Degree in Biological Sciences, Biochemistry, or Neuroscience
• Demonstrated record of academic achievement
• Past experience in basic science research
• Highly motivated and organized
• Strong work ethic
• GPA >3.5
• Preferred, not required: Prior experience with zebrafish or other aquaculture experienceApplication Instructions:
Send resume, cover letter describing interest in the position, unofficial transcript, and two letters of recommendation to firstname.lastname@example.org. Posted: Feb 2017
Using big data to improve the world’s health
The Institute for Health Metrics and Evaluation at the University of Washington offers a Post-Bachelor Fellowship in Global Health that combines a full-time professional position, academic research, and education with progressive on-the-job training and mentoring from a renowned group of professors. As a PBF, you will join a community of passionate researchers using creativity to solve complex global health problems. This program provides Post-Bachelor Fellows the option to pursue a fully funded Master of Public Health degree at the University of Washington.
Questions? Contact email@example.com. https://www.healthdata.org/post-bachelor-fellowship
Institute for Health Metrics and Evaluation, University of Washington
2301 5th Avenue, Suite 600, Seattle, WA 98121. Posted Feb 2017